|
KMID : 0545120040140051086
|
|
Journal of Microbiology and Biotechnology
2004 Volume.14 No. 5 p.1086 ~ p.1088
|
|
|
Inhibition of Epstein-Barr Virus by the Triterpenoid Betulin Diphosphate and Uvaol
|
|
Muhammad A
Carlson RM/Krasutsky P/Karim MRU
|
|
|
Abstract
|
|
|
|
Betulin a pentacyclic triterpenoid isolated from the bark of Betula papyrifera. Laboratory synthesized structural analogs were tested for antiviral activities against Epstein-Barr Virus (EBV) by immunofluorescent antiviral assay. Among the several analogs tested betulin 328-diphosphate and uvaol exhibited significant antiviral activities against EBV. The EC50 of betulin 328-diphosphate and uvaol was found to be 0.6 μM and 0.7 μM respectively.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|